A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection

The detection of malaria parasite (plasmodium falciparum) is investigated by using a novel photoacoustics (PA) excited surface acoustic wave (SAW) sensor. The SAW sensor is designed to resonant around 10 MHz and is fabricated by using standard two-step photolithography. The photoacoustic PA-SAW sens...

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Main Authors: Wang, Shaomeng, Yang, Chuanshi, Preiser, Peter, Zheng, Yuanjin
Other Authors: School of Electrical and Electronic Engineering
Format: Article
Language:English
Published: 2022
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Online Access:https://hdl.handle.net/10356/155309
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1553092022-03-18T01:07:01Z A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection Wang, Shaomeng Yang, Chuanshi Preiser, Peter Zheng, Yuanjin School of Electrical and Electronic Engineering School of Biological Sciences Engineering::Electrical and electronic engineering Photoacoustic Malaria Parasite The detection of malaria parasite (plasmodium falciparum) is investigated by using a novel photoacoustics (PA) excited surface acoustic wave (SAW) sensor. The SAW sensor is designed to resonant around 10 MHz and is fabricated by using standard two-step photolithography. The photoacoustic PA-SAW sensing system is composed of a SAW sensor, cooperating with a pulsed laser, a neutral density filter, a convex lens, two analog front ends (AFEs) and an oscilloscope. PA signals and their spectrums of different materials are obtained for calibration, and the PA signals of normal blood and infected blood are chaterized through the PA-SAW sensing system, subsequently. The infected blood with cultured ring-stage malaria parasites concentrations of 1% can be detected. The demonstration shows that the PA-SAW sensor has good potential in the diagnosis of malaria at early stage. Nanyang Technological University This work was supported by the NTUHealth-LKCMedince-NHG under Grant IDPOCT17002. 2022-03-18T01:07:01Z 2022-03-18T01:07:01Z 2020 Journal Article Wang, S., Yang, C., Preiser, P. & Zheng, Y. (2020). A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection. IEEE Transactions On Circuits and Systems II: Express Briefs, 67(5), 881-885. https://dx.doi.org/10.1109/TCSII.2020.2981148 1549-7747 https://hdl.handle.net/10356/155309 10.1109/TCSII.2020.2981148 2-s2.0-85084404238 5 67 881 885 en IDPOCT17002 IEEE Transactions on Circuits and Systems II: Express Briefs © 2020 IEEE. All rights reserved.
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Engineering::Electrical and electronic engineering
Photoacoustic
Malaria Parasite
spellingShingle Engineering::Electrical and electronic engineering
Photoacoustic
Malaria Parasite
Wang, Shaomeng
Yang, Chuanshi
Preiser, Peter
Zheng, Yuanjin
A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection
description The detection of malaria parasite (plasmodium falciparum) is investigated by using a novel photoacoustics (PA) excited surface acoustic wave (SAW) sensor. The SAW sensor is designed to resonant around 10 MHz and is fabricated by using standard two-step photolithography. The photoacoustic PA-SAW sensing system is composed of a SAW sensor, cooperating with a pulsed laser, a neutral density filter, a convex lens, two analog front ends (AFEs) and an oscilloscope. PA signals and their spectrums of different materials are obtained for calibration, and the PA signals of normal blood and infected blood are chaterized through the PA-SAW sensing system, subsequently. The infected blood with cultured ring-stage malaria parasites concentrations of 1% can be detected. The demonstration shows that the PA-SAW sensor has good potential in the diagnosis of malaria at early stage.
author2 School of Electrical and Electronic Engineering
author_facet School of Electrical and Electronic Engineering
Wang, Shaomeng
Yang, Chuanshi
Preiser, Peter
Zheng, Yuanjin
format Article
author Wang, Shaomeng
Yang, Chuanshi
Preiser, Peter
Zheng, Yuanjin
author_sort Wang, Shaomeng
title A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection
title_short A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection
title_full A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection
title_fullStr A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection
title_full_unstemmed A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection
title_sort photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection
publishDate 2022
url https://hdl.handle.net/10356/155309
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