A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection
The detection of malaria parasite (plasmodium falciparum) is investigated by using a novel photoacoustics (PA) excited surface acoustic wave (SAW) sensor. The SAW sensor is designed to resonant around 10 MHz and is fabricated by using standard two-step photolithography. The photoacoustic PA-SAW sens...
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sg-ntu-dr.10356-1553092022-03-18T01:07:01Z A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection Wang, Shaomeng Yang, Chuanshi Preiser, Peter Zheng, Yuanjin School of Electrical and Electronic Engineering School of Biological Sciences Engineering::Electrical and electronic engineering Photoacoustic Malaria Parasite The detection of malaria parasite (plasmodium falciparum) is investigated by using a novel photoacoustics (PA) excited surface acoustic wave (SAW) sensor. The SAW sensor is designed to resonant around 10 MHz and is fabricated by using standard two-step photolithography. The photoacoustic PA-SAW sensing system is composed of a SAW sensor, cooperating with a pulsed laser, a neutral density filter, a convex lens, two analog front ends (AFEs) and an oscilloscope. PA signals and their spectrums of different materials are obtained for calibration, and the PA signals of normal blood and infected blood are chaterized through the PA-SAW sensing system, subsequently. The infected blood with cultured ring-stage malaria parasites concentrations of 1% can be detected. The demonstration shows that the PA-SAW sensor has good potential in the diagnosis of malaria at early stage. Nanyang Technological University This work was supported by the NTUHealth-LKCMedince-NHG under Grant IDPOCT17002. 2022-03-18T01:07:01Z 2022-03-18T01:07:01Z 2020 Journal Article Wang, S., Yang, C., Preiser, P. & Zheng, Y. (2020). A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection. IEEE Transactions On Circuits and Systems II: Express Briefs, 67(5), 881-885. https://dx.doi.org/10.1109/TCSII.2020.2981148 1549-7747 https://hdl.handle.net/10356/155309 10.1109/TCSII.2020.2981148 2-s2.0-85084404238 5 67 881 885 en IDPOCT17002 IEEE Transactions on Circuits and Systems II: Express Briefs © 2020 IEEE. All rights reserved. |
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Engineering::Electrical and electronic engineering Photoacoustic Malaria Parasite Wang, Shaomeng Yang, Chuanshi Preiser, Peter Zheng, Yuanjin A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection |
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The detection of malaria parasite (plasmodium falciparum) is investigated by using a novel photoacoustics (PA) excited surface acoustic wave (SAW) sensor. The SAW sensor is designed to resonant around 10 MHz and is fabricated by using standard two-step photolithography. The photoacoustic PA-SAW sensing system is composed of a SAW sensor, cooperating with a pulsed laser, a neutral density filter, a convex lens, two analog front ends (AFEs) and an oscilloscope. PA signals and their spectrums of different materials are obtained for calibration, and the PA signals of normal blood and infected blood are chaterized through the PA-SAW sensing system, subsequently. The infected blood with cultured ring-stage malaria parasites concentrations of 1% can be detected. The demonstration shows that the PA-SAW sensor has good potential in the diagnosis of malaria at early stage. |
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School of Electrical and Electronic Engineering |
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School of Electrical and Electronic Engineering Wang, Shaomeng Yang, Chuanshi Preiser, Peter Zheng, Yuanjin |
format |
Article |
author |
Wang, Shaomeng Yang, Chuanshi Preiser, Peter Zheng, Yuanjin |
author_sort |
Wang, Shaomeng |
title |
A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection |
title_short |
A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection |
title_full |
A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection |
title_fullStr |
A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection |
title_full_unstemmed |
A photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection |
title_sort |
photoacoustic-surface-acoustic-wave sensor for ring-stage malaria parasite detection |
publishDate |
2022 |
url |
https://hdl.handle.net/10356/155309 |
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1728433417266135040 |