Age-dependent transcriptional and epigenetic alterations in mouse hepatocytes

Aging is associated with declining body function and heightened risks of various diseases. The liver is the largest solid internal organ responsible for functions ranging from metabolism to detoxification. Hepatocytes perform most liver functions and hepatocyte polyploidization is a characteristic f...

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Bibliographic Details
Main Author: Sharma, Ankur
Other Authors: Amartya Sanyal
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/155390
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Institution: Nanyang Technological University
Language: English