Age-dependent transcriptional and epigenetic alterations in mouse hepatocytes

• المؤلف الرئيسي: Sharma, Ankur
• مؤلفون آخرون: Amartya Sanyal
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2022
• الموضوعات: Science::Biological sciences::Biochemistry; Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/155390

Aging is associated with declining body function and heightened risks of various diseases. The liver is the largest solid internal organ responsible for functions ranging from metabolism to detoxification. Hepatocytes perform most liver functions and hepatocyte polyploidization is a characteristic f...