Modification of triphenylphosphonium lipophilic cations for mitochondrial delivery
Triphenylphosphonium (TPP+) moieties, when conjugated to a molecule of interest, results in greater mitochondrial accumulation relative to the unconjugated cargo. However, while TPP+ moieties are known to be effective at conferring mitochondrial-targeting abilities to molecules, modifications to the...
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| 格式: | Thesis-Doctor of Philosophy |
| 語言: | English |
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Nanyang Technological University
2022
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| 主題: | |
| 在線閱讀: | https://hdl.handle.net/10356/155725 |
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| 機構: | Nanyang Technological University |
| 語言: | English |