Splicing role of PRPF40A/B paralogs in human myeloid cells
PRPF40A and PRPF40B are the human orthologs of the essential yeast splicing factor Prp40, however their splicing role is not clearly understood. The expression of PRPF40A and PRPF40B is high and low respectively in acute myeloid leukemia (AML) as compared to solid tumors. This study explored the spl...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2022
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| Online Access: | https://hdl.handle.net/10356/155738 |
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| Institution: | Nanyang Technological University |
| Language: | English |