Investigating the role of phosphorylated regulatory light chains during heart failure progression

It is established that enhanced Regulatory Light Chain (RLC) phosphorylation in muscle improves its contractility. Incidentally, it is observed that the levels are enhanced during the compensatory phase of heart failure (HF) and reduced in the decompensatory phase, where muscle contractility is c...

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Bibliographic Details
Main Author: Markandran, Kasturi
Other Authors: Christine Cheung
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/155766
https://doi.org/10.3390/ijms23010088
https://doi.org/10.3390/ijms22094351
https://doi.org/10.1002/cpz1.221
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Institution: Nanyang Technological University
Language: English