Selective thrombosis of tumor for enhanced hypoxia-activated prodrug therapy

• Main Authors: Ma, Zhaoyu, Zhang, Yifan, Dai, Xinxin, Zhang, Weiyun, Mohamed F. Foda, Zhang, Jin, Zhao, Yanli, Han, Heyou
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Cancer Treatment; Metal–Organic Framework
• Online Access: https://hdl.handle.net/10356/155941
• Institution: Nanyang Technological University

One of the main challenges for tumor vascular infarction in combating cancer lies in failing to produce sustained complete thrombosis. Inspired by the capability of vascular infarction in blocking the delivery of oxygen to aggravate tumor hypoxia, we herein present the performance of selective tumor...