3D automated quantification of epidermal thickness and dermal heterogeneity in high-definition optical coherence tomography: Illustrative utility in morphea

• Main Authors: Lim, Gim Hui, Yow, Ai Ping, Zhao, Xiahong, Wong, Damon Wing Kee, Tey, Hong Liang
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Chemical engineering; Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics; Optical Coherence Tomography; Morphea; Skin
• Online Access: https://hdl.handle.net/10356/156206
• Institution: Nanyang Technological University

Scleroderma is the most common form of fibrotic disease involving the skin, and the subtype that only affects the skin is known as morphea. The conventional investigation for cutaneous fibrotic diseases is skin biopsy, an invasive ex vivo procedure. Typically, another biopsy of adjacent normal skin...