Nanopillar-guided subnuclear deformations in tumor cells

• Main Author: Zeng, Yongpeng
• Other Authors: Zhao Wenting
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Engineering::Nanotechnology
• Online Access: https://hdl.handle.net/10356/156207
• Institution: Nanyang Technological University

Subnuclear shape irregularities, including folding and grooves of the nuclear envelope, function as a routine marker in the diagnosis and prognosis of many cancer types and show strong correlation with diverse pathological alterations. However, their assessment is primarily relying on qualitative vi...