Effects of wild type Serum Amyloid A1.1 and its derivative proteins on the cholesterol efflux activity

• Main Author: Lim, Wan'e
• Other Authors: School of Biological Sciences
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/15684
• Institution: Nanyang Technological University

Serum Amyloid A (SAA) is known to be important in atherogenesis although the mechanisms are unclear. It is shown to promote cholesterol efflux activity of cells in several studies and may prevent atherosclerosis by promoting cholesterol efflux in foam cells of the atherosclerotic lesions. Therefore,...