High glucose restraint of acetylcholine-induced keratinocyte epithelial-mesenchymal transition is mitigated by p38 inhibition

• Main Authors: Tan, Mark Wei Yi, Tan, Wei Ren, Kong, Ze Qing, Toh, Jun Hong, Wee, Jonathan Wei Kiat, Teo, Erica Mei Ling, Cheng, Hong Sheng, Wang, Xiaomeng, Tan, Nguan Soon
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2022
• 主題: Science::Biological sciences; Acetylcholine; Cell Function
• 在線閱讀: https://hdl.handle.net/10356/157036
• 機構: Nanyang Technological University

Non-neuronal acetylcholine (Ach) plays important roles in various aspects of cell biology and homeostasis outside the neural system. Keratinocytes (KCs) have a functional cholinergic mechanism, suggesting that they respond to Ach. However, the physiological role and mechanism by which Ach modulates...