Examining the immunoreactivities of the receptor-binding domain of SARS-CoV-2 spike proteins using a panel of human monoclonal antibodies

• Main Author: Tan, Jie Ling
• Other Authors: Richard J Sugrue
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences::Microbiology::Virology; Science::Biological sciences::Microbiology::Immunology
• Online Access: https://hdl.handle.net/10356/157131
• Institution: Nanyang Technological University

Previously, a panel of human monoclonal antibodies (hMAbs) (PD5, SC23, and PD4) were isolated from convalescent patients to evaluate their therapeutic potential in the treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the binding domains of these antibodies have not been...