Analysis of pili heterogeneity and regulation in Enterococcus faecalis

• Main Author: Quek, Keefe Qingyao
• Other Authors: Kimberly Kline
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences::Microbiology::Bacteria
• Online Access: https://hdl.handle.net/10356/157136
• Institution: Nanyang Technological University

Enterococcus faecalis undergoes phase variation to regulate the number of cells expressing pili, a characteristic virulence factor, allowing it to evade a host immune response. Understanding phase variation is important for the development of therapeutic strategies against pili. Preliminary RNA sequ...