Examining the expression of Guanylate binding protein 1 during respiratory syncytial virus infection in permissible cell types

• Main Author: Tan, Jevon Shin Yong
• Other Authors: Richard J Sugrue
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences::Microbiology::Virology
• Online Access: https://hdl.handle.net/10356/157333
• Institution: Nanyang Technological University

Genetic studies have shown Guanylate binding protein (GBP-1) to be highly upregulated very early on in Respiratory Syncytial Virus (RSV) infection. However, molecular events that demonstrate the role of GBP-1 in viral progression and its involvement in the host anti-viral signalling responses still...