Role of lipid droplets and FITM2 in beta-cell physiology and pathophysiology

Hyperlipidemia is a known driving factor of T2DM, with saturated fatty acids (SFAs) pinpointed as the causation of β cell failure. Hence, intracellular handling of these SFAs, in β cells, was thought to be vital in preventing the loss of its function. The biogenesis of lipid droplets (LDs) forms an...

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Bibliographic Details
Main Author: Ho, Calvin Qing Wei
Other Authors: Yusuf Ali
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/158047
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Institution: Nanyang Technological University
Language: English
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