Development and application of genetic engineering tools

SNPs in the genomic DNA are linked to numerous diseases. In these cases, the disease and healthy alleles differ by a single DNA base. Using CRISPR-Cas9 base editors, it is possible to modify SNPs by converting the targeted disease-related DNA base into another base. CGBEs are different from CBEs and...

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Bibliographic Details
Main Author: Teo, Yi Yong
Other Authors: Tan Meng How
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/159073
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Institution: Nanyang Technological University
Language: English