Inactivation of common airborne antigens by perfluoroalkyl chemicals modulates early life allergic asthma

• Main Authors: Wang, Mengjing, Li, Qianqian, Hou, Meifang, Chan, Louisa L. Y., Liu, Meng, Ter, Soo Kai, Dong, Ting, Xia, Yun, Chotirmall, Sanjay Haresh, Fang, Mingliang
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Early Life Exposure; Pulmonary Immunomodulation
• Online Access: https://hdl.handle.net/10356/159602
• Institution: Nanyang Technological University

Allergic asthma, driven by T helper 2 cell-mediated immune responses to common environmental antigens, remains the most common respiratory disease in children. Perfluorinated chemicals (PFCs) are environmental contaminants of great concern, because of their wide application, persistence in the envir...