Circulating microRNA breast cancer biomarker detection in patient sera with surface plasmon resonance imaging biosensor

• Main Authors: Wong, Chi Lok, Loke, Sau Yeen, Lim, Hann Qian, Balasundaram, Ghayathri, Chan, Patrick, Chong, Bee Kiang, Tan, Ern Yu, Lee, Ann Siew Gek, Olivo, Malini
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Breast Cancer Biomarker; Circulating miRNA
• Online Access: https://hdl.handle.net/10356/159651
• Institution: Nanyang Technological University

In this article, we report for the first time, the detection of circulating miRNA as a breast cancer biomarker in patient sera using surface plasmon resonance imaging biosensor. The advantage of this approach lies in the rapid, label-free and sensitive detection. The sensor excites plasmonic resonan...