Elucidating how different amphipathic stabilizers affect BSA protein conformational properties and adsorption behavior

• Main Authors: Ma, Gamaliel Junren, Ferhan, Abdul Rahim, Jackman, Joshua A., Cho, Nam-Joon
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Materials; Surfectants; Surfaces
• Online Access: https://hdl.handle.net/10356/159686
• Institution: Nanyang Technological University

Natural proteins such as bovine serum albumin (BSA) are readily extracted from biological fluids and widely used in various applications such as drug delivery and surface coatings. It is standard practice to dope BSA proteins with an amphipathic stabilizer, most commonly fatty acids, during purifica...