Building blocks to the future of regenerative medicine: organoid bioprinting
Despite being valuable models of study, organoids can be limited in their usefulness due to their small millimeter scale. In a letter in Nature Materials, Lutolf and his team at the Ecole Polytechnique Fédérale de Lausanne (EPFL) designed an innovative three-dimensional (3D) bioprinting concept that...
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| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/159786 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Despite being valuable models of study, organoids can be limited in their usefulness due to their small millimeter scale. In a letter in Nature Materials, Lutolf and his team at the Ecole Polytechnique Fédérale de Lausanne (EPFL) designed an innovative three-dimensional (3D) bioprinting concept that they termed bioprinting-assisted tissue emergence (BATE), overcoming organoids limits by using them as building blocks to mimic macroscale in vivo tissue. Their novel approach, combining the precision of bioprinting with the self-organizing potential of organoids, opens the path for new breakthroughs in regenerative medicine because of the potential of the engineered tissue to mimic native organ boundaries as well as tissue-tissue interactions. |
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