Solvent-induced conformational tuning of lysozyme protein adlayers on silica surfaces: a QCM-D and LSPR study

• Main Authors: Yoon, Bo Kyeong, Ma, Gamaliel Junren, Park, Hyeonjin, Ferhan, Abdul Rahim, Cho, Nam-Joon, Jackman, Joshua A.
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Materials; Lysozyme; Protein Adsorption
• Online Access: https://hdl.handle.net/10356/159863
• Institution: Nanyang Technological University

There is broad interest in functionalizing solid surfaces with lysozyme, which is a widely studied antimicrobial protein. To date, most efforts have focused on developing more effective immobilization schemes to promote lysozyme attachment in fully aqueous conditions, while there remains an outstand...