Genetically modified bacteria for targeted phototherapy of tumor

• Main Authors: Deng, Xiangyu, Yang, Wenbo, Shao, Zengwu, Zhao, Yanli
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Assembled Systems; Genetically Modified Bacteria
• Online Access: https://hdl.handle.net/10356/159871
• Institution: Nanyang Technological University

Live attenuated bacteria have been used as target vehicles for genetic therapy of malignant carcinoma because they can be reprogrammed by following simple genetic rules and have the ability to target tumor hypoxic region. In this research, noninvasive Escherichia coli (E. Coli) is genetically modifi...