Prefrontal-hippocampus plasticity reinstated by an enriched environment during stress

• Main Authors: Wu, You, Mitra, Rupshi
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Hippocampus; Long-Term Potentiation
• Online Access: https://hdl.handle.net/10356/159954
• Institution: Nanyang Technological University

Chronic stress causes dendritic atrophy of neurons within the hippocampus and medial prefrontal cortex. In this report, we show that chronic stress leads to reduced long-term potentiation in the pathway from the hippocampus to the medial prefrontal cortex of rats; and that such reduction is rescued...