Adaptation to an amoeba host leads to Pseudomonas aeruginosa isolates with attenuated virulence

• Main Authors: Leong, Wai, Poh, Wee Han, Williams, Jonathan, Lutz, Carla, Hoque, M. Mozammel, Poh, Yan Hong, Yee, Benny Yeo Ken, Chua, Cliff, Givskov, Michael, Sanderson-Smith, Martina, Rice, Scott A., McDougald, Diane
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Pseudomonas; Biofilm
• Online Access: https://hdl.handle.net/10356/160067
• Institution: Nanyang Technological University

The opportunistic pathogen Pseudomonas aeruginosa is ubiquitous in the environment, and in humans, it is capable of causing acute or chronic infections. In the natural environment, predation by bacterivorous protozoa represents a primary threat to bacteria. Here, we determined the impact of long-ter...