Self-assembly of dendritic DNA into a hydrogel: application in three-dimensional cell culture

• المؤلفون الرئيسيون: Wu, Jingyuan, Liyarita, Bella Rosa, Zhu, Haishuang, Liu, Ming, Hu, Xiao, Shao, Fangwei
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2022
• الموضوعات: Engineering::Materials; DNA Hydrogel; Cell Spheroids
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/160082
• المؤسسة: Nanyang Technological University

With inherent biocompatibility, biodegradability, and unique programmability, hydrogels with a DNA framework show great potential in three-dimensional (3D) cell culture. Here, a DNA hydrogel was assembled by a dendritic DNA with four branches. The hydrogel showed tunable mechanical strength and reve...