Comparative evaluations of bulk seeded protein crystallization in batch versus continuous slug flow crystallizers

• Main Authors: Pu, Siyu, Hadinoto, Kunn
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Chemical engineering; Continuous Crystallization; Protein Crystallization
• Online Access: https://hdl.handle.net/10356/160115
• Institution: Nanyang Technological University

The present work evaluated for the first time the use of continuous slug flow crystallizer (CSFC) in bulk seeded protein crystallization, using lysozyme (LYZ) as the model protein. LYZ crystals pre-prepared in batch crystallizer were used as seeds. The crystallization was performed at supersaturatio...