Lipidomic trajectories characterize delayed mucosal wound healing in quiescent ulcerative colitis and identify potential novel therapeutic targets

• Main Authors: Bjerrum, Jacob Tveiten, Wang, Yulan, Zhang, Jingtao, Riis, Lene Buhl, Nielsen, Ole Haagen, Seidelin, Jakob Benedict
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Eicosanoids; Inflammatory Bowel Disease
• Online Access: https://hdl.handle.net/10356/160159
• Institution: Nanyang Technological University

Improving the long-term prognosis of ulcerative colitis (UC) requires sustained deep mucosal colonic healing with histologic remission, making the study of colonic tissue regeneration essential. In experimental colitis models, lipid metabolites are recognized as pivotal components of this process. T...