A H₂O₂-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging

• Main Authors: Chen, Junjie, Chen, Longqi, Wu, Yinglong, Fang, Yichang, Zeng, Fang, Wu, Shuizhu, Zhao, Yanli
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; Hydrogen Peroxide; Optical Imaging
• Online Access: https://hdl.handle.net/10356/160405
• Institution: Nanyang Technological University

Developing high-quality NIR-II fluorophores (emission in 1000-1700 nm) for in vivo imaging is of great significance. Benzothiadiazole-core fluorophores are an important class of NIR-II dyes, yet ongoing limitations such as aggregation-caused quenching in aqueous milieu and non-activatable response a...