Zyxin is involved in fibroblast rigidity sensing and durotaxis

• Main Authors: Yip, Ai Kia, Zhang, Songjing, Chong, Lor Huai, Cheruba, Elsie, Woon, Jessie Yong Xing, Chua, Theng Xuan, Goh, Corinna Jie Hui, Yang, Haibo, Tay, Chor Yong, Koh, Cheng-Gee, Chiam, Keng-Hwee
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Zyxin; Focal Adhesion
• Online Access: https://hdl.handle.net/10356/160518
• Institution: Nanyang Technological University

Focal adhesions (FAs) are specialized structures that enable cells to sense their extracellular matrix rigidity and transmit these signals to the interior of the cells, bringing about actin cytoskeleton reorganization, FA maturation, and cell migration. It is known that cells migrate towards regions...