Mechanistic aspects of the evolution of 3D cholesterol crystallites in a supported lipid membrane via a quartz crystal microbalance with dissipation monitoring

• Main Authors: Ma, Gamaliel Junren, Zhdanov, Vladimir P., Park, Soohyun, Sut, Tun Naw, Cho, Nam-Joon
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Materials; Cholesterol; Crystallization
• Online Access: https://hdl.handle.net/10356/160577
• Institution: Nanyang Technological University

The irreversible formation of cholesterol monohydrate crystals within biological membranes is the leading cause of various diseases, including atherosclerosis. Understanding the process of cholesterol crystallization is fundamentally important and could also lead to the development of improved thera...