In vivo investigation of polymer-ceramic PCL/HA and PCL/β-TCP 3D composite scaffolds and electrical stimulation for bone regeneration

• Main Authors: Helaehil, Júlia Venturini, Lourenço, Carina Basqueira, Huang, Boyang, Helaehil, Luiza Venturini, de Camargo, Isaque Xavier, Chiarotto, Gabriela Bortolança, Santamaria-Jr, Milton, Bártolo, Paulo, Caetano, Guilherme Ferreira
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Mechanical engineering; Hydroxyapatite; Additive Manufacturing
• Online Access: https://hdl.handle.net/10356/160605
• Institution: Nanyang Technological University

Critical bone defects are a major clinical challenge in reconstructive bone surgery. Polycaprolactone (PCL) mixed with bioceramics, such as hydroxyapatite (HA) and tricalcium phosphate (TCP), create composite scaffolds with improved biological recognition and bioactivity. Electrical stimulation (ES)...