CD27hiCD38hi plasmablasts are activated B cells of mixed origin with distinct function

• Main Authors: Rouers, Angeline, Appanna, Ramapraba, Chevrier, Marion, Lum, Josephine, Lau, Mai Chan, Tan, Lingqiao, Loy, Thomas, Tay, Alicia, Sethi, Raman, Sathiakumar, Durgalakshmi, Kaur, Kaval, Böhme, Julia, Leo, Yee-Sin, Renia, Laurent, Howland, Shanshan W, Singhal, Amit, Chen, Jinmiao, Fink, Katja
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Cell Biology; Immunology
• Online Access: https://hdl.handle.net/10356/160689
• Institution: Nanyang Technological University

Clinically important broadly reactive B cells evolve during multiple infections, with B cells re-activated after secondary infection differing from B cells activated after a primary infection. Here we studied CD27highCD38high plasmablasts from patients with a primary or secondary dengue virus infect...