A facile and scalable hydrogel patterning method for microfluidic 3D cell culture and spheroid-in-gel culture array

• Main Authors: Su, Chengxun, Chuah, Yon Jin, Ong, Hong Boon, Tay, Hui Min, Dalan, Rinkoo, Hou, Han Wei
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Mechanical engineering; Hydrogel Patterning; 3D Cell Culture
• Online Access: https://hdl.handle.net/10356/160713
• Institution: Nanyang Technological University

Incorporation of extracellular matrix (ECM) and hydrogel in microfluidic 3D cell culture platforms is important to create a physiological microenvironment for cell morphogenesis and to establish 3D co-culture models by hydrogel compartmentalization. Here, we describe a simple and scalable ECM patter...