Associations of living arrangements with symptoms and functioning in schizophrenia

Background: Living arrangements and accommodation are closely related, but no study had concurrently investigated their associations with outcomes in schizophrenia. This study seeks to describe and compare sociodemographic, clinical and functioning profiles of people with schizophrenia in different...

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Main Authors: Ang, Mei San, Rekhi, Gurpreet, Lee, Jimmy
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
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Online Access:https://hdl.handle.net/10356/160728
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Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-160728
record_format dspace
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
Schizophrenia
Living Arrangements
spellingShingle Science::Medicine
Schizophrenia
Living Arrangements
Ang, Mei San
Rekhi, Gurpreet
Lee, Jimmy
Associations of living arrangements with symptoms and functioning in schizophrenia
description Background: Living arrangements and accommodation are closely related, but no study had concurrently investigated their associations with outcomes in schizophrenia. This study seeks to describe and compare sociodemographic, clinical and functioning profiles of people with schizophrenia in different living arrangements and accommodation, and to examine the associations of living arrangements and accommodation with symptomatic remission and functioning. Methods: Community dwelling outpatients with schizophrenia (n = 276) were inquired on living arrangements, accommodation, socio-demographics and assessed on the Positive and Negative Syndrome Scale (PANSS) and the Social and Occupational Functioning Scale (SOFAS). Socio-demographics, symptoms and functioning of outpatients in different living arrangements and accommodation were compared. Symptomatic remission was investigated using logistic regression with living arrangements, socio-demographics and clinical variables as independent variables. Functioning was investigated using multiple regression with the same set of independent variables and the addition of PANSS factors. The same analyses were conducted with accommodation as independent variable. Results: 185 (67.03%) participants lived with family and 195 (70.65%) participants lived in owned accommodation. People living with their spouses had significantly higher SOFAS, lower PANSS Total and PANSS Positive than people living with family, independently, or in rehabilitation centres. They also had lower PANSS Negative than people living with family and a higher likelihood to have achieved symptomatic remission. Types of accommodation was not associated with symptoms, symptomatic remission, and functioning. Conclusion: Living arrangements, but not types of accommodation, were associated with symptoms and functioning in schizophrenia. Family education and support is important to help maintain a conducive environment for people with schizophrenia. People living independently may need more support.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Ang, Mei San
Rekhi, Gurpreet
Lee, Jimmy
format Article
author Ang, Mei San
Rekhi, Gurpreet
Lee, Jimmy
author_sort Ang, Mei San
title Associations of living arrangements with symptoms and functioning in schizophrenia
title_short Associations of living arrangements with symptoms and functioning in schizophrenia
title_full Associations of living arrangements with symptoms and functioning in schizophrenia
title_fullStr Associations of living arrangements with symptoms and functioning in schizophrenia
title_full_unstemmed Associations of living arrangements with symptoms and functioning in schizophrenia
title_sort associations of living arrangements with symptoms and functioning in schizophrenia
publishDate 2022
url https://hdl.handle.net/10356/160728
_version_ 1759854600411676672
spelling sg-ntu-dr.10356-1607282023-03-05T16:53:07Z Associations of living arrangements with symptoms and functioning in schizophrenia Ang, Mei San Rekhi, Gurpreet Lee, Jimmy Lee Kong Chian School of Medicine (LKCMedicine) Institute of Mental Health Science::Medicine Schizophrenia Living Arrangements Background: Living arrangements and accommodation are closely related, but no study had concurrently investigated their associations with outcomes in schizophrenia. This study seeks to describe and compare sociodemographic, clinical and functioning profiles of people with schizophrenia in different living arrangements and accommodation, and to examine the associations of living arrangements and accommodation with symptomatic remission and functioning. Methods: Community dwelling outpatients with schizophrenia (n = 276) were inquired on living arrangements, accommodation, socio-demographics and assessed on the Positive and Negative Syndrome Scale (PANSS) and the Social and Occupational Functioning Scale (SOFAS). Socio-demographics, symptoms and functioning of outpatients in different living arrangements and accommodation were compared. Symptomatic remission was investigated using logistic regression with living arrangements, socio-demographics and clinical variables as independent variables. Functioning was investigated using multiple regression with the same set of independent variables and the addition of PANSS factors. The same analyses were conducted with accommodation as independent variable. Results: 185 (67.03%) participants lived with family and 195 (70.65%) participants lived in owned accommodation. People living with their spouses had significantly higher SOFAS, lower PANSS Total and PANSS Positive than people living with family, independently, or in rehabilitation centres. They also had lower PANSS Negative than people living with family and a higher likelihood to have achieved symptomatic remission. Types of accommodation was not associated with symptoms, symptomatic remission, and functioning. Conclusion: Living arrangements, but not types of accommodation, were associated with symptoms and functioning in schizophrenia. Family education and support is important to help maintain a conducive environment for people with schizophrenia. People living independently may need more support. Ministry of Health (MOH) National Medical Research Council (NMRC) Published version This study is supported by the Singapore Ministry of Health’s National Medical Research Council under the Centre Grant Programme (Grant No.: NMRC/CG/004/2013, NMRC/CG/M002/2017_IMH). 2022-08-01T08:49:44Z 2022-08-01T08:49:44Z 2021 Journal Article Ang, M. S., Rekhi, G. & Lee, J. (2021). Associations of living arrangements with symptoms and functioning in schizophrenia. BMC Psychiatry, 21(1), 497-. https://dx.doi.org/10.1186/s12888-021-03488-5 1471-244X https://hdl.handle.net/10356/160728 10.1186/s12888-021-03488-5 34635064 2-s2.0-85117203264 1 21 497 en NMRC/CG/004/2013 NMRC/CG/M002/2017_IMH BMC Psychiatry © 2021 The Authors. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. application/pdf