Interpenetrating network of alginate-human adipose extracellular matrix hydrogel for islet cells encapsulation

• Main Authors: Wang, Jun Kit, Cheam, Nicole Mein Ji, Irvine, Scott Alexander, Tan, Nguan Soon, Venkatraman, Subbu, Tay, Chor Yong
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Materials; Alginate; Interpenetrating Polymer Networks
• Online Access: https://hdl.handle.net/10356/161139
• Institution: Nanyang Technological University

Transplantation of microencapsulated islet cells holds great potential for the treatment of type 1 diabetes mellitus. However, its clinical translation is hampered by the peri-transplantation loss of islet viability and functionality in the microcapsules. In this work, a novel islet cells biomimetic...