Design and synthesis of a bifunctional linker for N-linked glycopeptide synthesis

• Main Author: Lin, Desmond Junjie
• Other Authors: Liu Xuewei
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Chemistry::Organic chemistry
• Online Access: https://hdl.handle.net/10356/161192
• Institution: Nanyang Technological University

N-linked glycopeptides and cyclic peptide are an important class of compounds. Many of these naturally occurring compounds possess therapeutic value which could be used for treating antimicrobial resistance infections. However, these compounds were under-utilized for drug discovery as it is difficul...