High frame rate (∼3 Hz) circular photoacoustic tomography using single-element ultrasound transducer aided with deep learning

• Main Authors: Rajendran, Praveenbalaji, Pramanik, Manojit
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Bioengineering; Photoacoustic Tomography; High Framerate Imaging
• Online Access: https://hdl.handle.net/10356/161291
• Institution: Nanyang Technological University

Significance: In circular scanning photoacoustic tomography (PAT), it takes several minutes to generate an image of acceptable quality, especially with a single-element ultrasound transducer (UST). The imaging speed can be enhanced by faster scanning (with high repetition rate light sources) and using multiple-USTs. However, artifacts arising from the sparse signal acquisition and low signal-to-noise ratio at higher scanning speeds limit the imaging speed. Thus, there is a need to improve the imaging speed of the PAT systems without hampering the quality of the PAT image. Aim: To improve the frame rate (or imaging speed) of the PAT system by using deep learning (DL). Approach: For improving the frame rate (or imaging speed) of the PAT system, we propose a novel U-Net-based DL framework to reconstruct PAT images from fast scanning data. Results: The efficiency of the network was evaluated on both single-and multiple-UST-based PAT systems. Both phantom and in vivo imaging demonstrate that the network can improve the imaging frame rate by approximately sixfold in single-UST-based PAT systems and by approximately twofold in multi-UST-based PAT systems. Conclusions: We proposed an innovative method to improve the frame rate (or imaging speed) by using DL and with this method, the fastest frame rate of ∼3 Hz imaging is achieved without hampering the quality of the reconstructed image.