Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19

Objectives: Following the emergence of the Delta variant of SARS-CoV-2 in Singapore, our hospital experienced a Delta-linked ward cluster. In this study, we review the enhanced strategies in preventing nosocomial transmission of COVID-19 following widespread community transmission of the Delta varia...

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Main Authors: Lim, Rachel Hui Fen, Htun, Htet Lin, Li, Anthony Lianjie, Guo, Huiling, Kyaw, Win Mar, Hein, Aung Aung, Ang, Brenda, Chow, Angela
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
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Online Access:https://hdl.handle.net/10356/161296
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1612962023-03-05T16:54:49Z Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19 Lim, Rachel Hui Fen Htun, Htet Lin Li, Anthony Lianjie Guo, Huiling Kyaw, Win Mar Hein, Aung Aung Ang, Brenda Chow, Angela Lee Kong Chian School of Medicine (LKCMedicine) Tan Tock Seng Hospital Saw Swee Hock School of Public Health, National University of Singapore Science::Medicine COVID-19 Delta Objectives: Following the emergence of the Delta variant of SARS-CoV-2 in Singapore, our hospital experienced a Delta-linked ward cluster. In this study, we review the enhanced strategies in preventing nosocomial transmission of COVID-19 following widespread community transmission of the Delta variant. Methods: We conducted a cohort study on exposures to unexpected COVID-19 cases for which contact tracing was initiated from June 2021 to October 2021. Strategies evaluated included upgraded personal protective equipment (PPE) and rostered routine testing (RRT) for staff and patients, surveillance of staff with acute respiratory illness (ARI), and expanded quarantining and testing for contacts of identified cases. Results: From 193 unexpected COVID-19 exposures, 2,573 staff, 542 patients, and 128 visitor contacts were traced. Four staff contacts subsequently had SARS-CoV-2 infection. Two were likely from exposure in community settings, whereas 2 had exposure to the same COVID-19 positive staff in the hospital, forming the only hospital cluster. One inpatient had a nosocomial infection, possibly from visitors. The SARS-CoV-2 detection rate among staff was 0.3% (of 11,200 staff) from biweekly RRT and 2.5% (of 3,675 staff) from ARI surveillance. Conclusion: Enhanced hospital measures, including upgraded PPE and RRT for staff and patients, staff sickness surveillance, and more rigorous management of contacts of COVID-19 cases, were likely to have reduced nosocomial transmission amid the Delta variant. Published version 2022-08-24T04:42:35Z 2022-08-24T04:42:35Z 2022 Journal Article Lim, R. H. F., Htun, H. L., Li, A. L., Guo, H., Kyaw, W. M., Hein, A. A., Ang, B. & Chow, A. (2022). Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19. International Journal of Infectious Diseases, 117, 139-145. https://dx.doi.org/10.1016/j.ijid.2022.01.069 1201-9712 https://hdl.handle.net/10356/161296 10.1016/j.ijid.2022.01.069 35124240 2-s2.0-85124843339 117 139 145 en International Journal of Infectious Diseases © 2022 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
COVID-19
Delta
spellingShingle Science::Medicine
COVID-19
Delta
Lim, Rachel Hui Fen
Htun, Htet Lin
Li, Anthony Lianjie
Guo, Huiling
Kyaw, Win Mar
Hein, Aung Aung
Ang, Brenda
Chow, Angela
Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19
description Objectives: Following the emergence of the Delta variant of SARS-CoV-2 in Singapore, our hospital experienced a Delta-linked ward cluster. In this study, we review the enhanced strategies in preventing nosocomial transmission of COVID-19 following widespread community transmission of the Delta variant. Methods: We conducted a cohort study on exposures to unexpected COVID-19 cases for which contact tracing was initiated from June 2021 to October 2021. Strategies evaluated included upgraded personal protective equipment (PPE) and rostered routine testing (RRT) for staff and patients, surveillance of staff with acute respiratory illness (ARI), and expanded quarantining and testing for contacts of identified cases. Results: From 193 unexpected COVID-19 exposures, 2,573 staff, 542 patients, and 128 visitor contacts were traced. Four staff contacts subsequently had SARS-CoV-2 infection. Two were likely from exposure in community settings, whereas 2 had exposure to the same COVID-19 positive staff in the hospital, forming the only hospital cluster. One inpatient had a nosocomial infection, possibly from visitors. The SARS-CoV-2 detection rate among staff was 0.3% (of 11,200 staff) from biweekly RRT and 2.5% (of 3,675 staff) from ARI surveillance. Conclusion: Enhanced hospital measures, including upgraded PPE and RRT for staff and patients, staff sickness surveillance, and more rigorous management of contacts of COVID-19 cases, were likely to have reduced nosocomial transmission amid the Delta variant.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Lim, Rachel Hui Fen
Htun, Htet Lin
Li, Anthony Lianjie
Guo, Huiling
Kyaw, Win Mar
Hein, Aung Aung
Ang, Brenda
Chow, Angela
format Article
author Lim, Rachel Hui Fen
Htun, Htet Lin
Li, Anthony Lianjie
Guo, Huiling
Kyaw, Win Mar
Hein, Aung Aung
Ang, Brenda
Chow, Angela
author_sort Lim, Rachel Hui Fen
title Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19
title_short Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19
title_full Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19
title_fullStr Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19
title_full_unstemmed Fending off Delta - hospital measures to reduce nosocomial transmission of COVID-19
title_sort fending off delta - hospital measures to reduce nosocomial transmission of covid-19
publishDate 2022
url https://hdl.handle.net/10356/161296
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