Inhibition of the quorum sensing system, elastase production and biofilm formation in pseudomonas aeruginosa by psammaplin A and bisaprasin

• Main Authors: Oluwabusola, Emmanuel T., Katermeran, Nursheena Parveen, Poh, Wee Han, Goh, Ben Teo Min, Tan, Lik Tong, Diyaolu, Oluwatofunmilayo, Tabudravu, Jioji, Ebel, Rainer, Rice, Scott A., Jaspars, Marcel
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Biological sciences; Marine Sponge; Psammaplin
• Online Access: https://hdl.handle.net/10356/161302
• Institution: Nanyang Technological University

Natural products derived from marine sponges have exhibited bioactivity and, in some cases, serve as potent quorum sensing inhibitory agents that prevent biofilm formation and attenuate virulence factor expression by pathogenic microorganisms. In this study, the inhibitory activity of the psammaplin...