A study of lipid-mediated clustering of oncogenic Ras proteins on cell membrane using nanotopography engineering

Dysregulation of Ras, a dominant oncogenic protein, in cell proliferation, differentiation, and survival contributes to ~20% of human cancers. Despite great efforts paid in identifying anti-Ras therapeutics for the past decades, it remains a challenging task to provide effective anti-Ras drugs for c...

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書目詳細資料
主要作者: Mu, Huanwen
其他作者: Zhao Wenting
格式: Thesis-Doctor of Philosophy
語言:English
出版: Nanyang Technological University 2022
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在線閱讀:https://hdl.handle.net/10356/161320
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