A study of lipid-mediated clustering of oncogenic Ras proteins on cell membrane using nanotopography engineering
Dysregulation of Ras, a dominant oncogenic protein, in cell proliferation, differentiation, and survival contributes to ~20% of human cancers. Despite great efforts paid in identifying anti-Ras therapeutics for the past decades, it remains a challenging task to provide effective anti-Ras drugs for c...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2022
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| Online Access: | https://hdl.handle.net/10356/161320 |
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| Institution: | Nanyang Technological University |
| Language: | English |