K-ras oncogene and p53 gene mutations in cholangiocarcinoma from Thai patients

• Main Authors: Songsak Petmitr, Somchai Pinlaor, Ampai Thousungnoen, Anant Karalak, Panata Migasena
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/18566

Paraffin embedded tisues from twenty Thai patients with intrahepatic cholangiocarcinomas were studied forK-ras gene mutations at codon 12,13 and 61 and for p53 gene mutations in exon 5 to 8 using polymerase chain reaction and thermal cycle sequencing. Results showed that point mutations at these reg...