Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of infection

• Main Authors: Gibson, Josie F., Bojarczuk, Aleksandra, Evans, Robert J., Kamuyango, Alfred Alinafe, Hotham, Richard, Lagendijk, Anne K., Hogan, Benjamin M., Ingham, Philip William, Renshaw, Stephen A., Johnston, Simon A.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Blood Vessel Occlusion; Cryptococcus Neoformans
• Online Access: https://hdl.handle.net/10356/161383
• Institution: Nanyang Technological University

Meningitis caused by infectious pathogens is associated with vessel damage and infarct formation, however the physiological cause is often unknown. Cryptococcus neoformans is a human fungal pathogen and causative agent of cryptococcal meningitis, where vascular events are observed in up to 30% of pa...