Systemic lactate elevation induced by tobacco smoking during rest and exercise is not associated with nicotine

• Main Authors: Sumartiningsih, Sri, Rahayu, Setya, Handoyo, Eko, Lin, Jung-Charng, Lim, Chin Leong, Starczewski, Michal, Fuchs, Philip X., Kuo, Chia-Hua
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Nicotine; Vaping
• Online Access: https://hdl.handle.net/10356/161405
• Institution: Nanyang Technological University

Lactate is a metabolite produced during anaerobic glycolysis for ATP resynthesis, which accumulates during hypoxia and muscle contraction. Tobacco smoking significantly increases blood lactate. Here we conducted a counter-balanced crossover study to examine whether this effect is associated with inh...