Maternal methamphetamine exposure influences behavioral sensitization and nucleus accumbens DNA methylation in subsequent generation

• Main Authors: Dong, Nan, Zhu, Jie, Wang, Rui, Wang, Shuai, Chen, Yanjiong, Wang, Changhe, Goh, Eyleen Lay Keow, Chen, Teng
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Methamphetamine; Maternal Exposure
• Online Access: https://hdl.handle.net/10356/161457
• Institution: Nanyang Technological University

The deleterious effects of methamphetamine (METH) exposure extend beyond abusers, and may potentially impact the vulnerability of their offspring in developing addictive behaviors. Epigenetic signatures have been implicated in addiction, yet the characteristics to identify prenatal METH abuse to off...