Localized degradation of neutrophil extracellular traps by photoregulated enzyme delivery for cancer immunotherapy and metastasis suppression

• Main Authors: Chen, Jiayuan, Hou, Shuai, Liang, Qing, He, Wenshan, Li, Ruiqi, Wang, Haihong, Zhu, Ying, Zhang, Biying, Chen, Lingjuan, Dai, Xiaofang, Zhang, Tao, Ren, Jinghua, Duan, Hongwei
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; Nanoparticles; Second Near-Infrared
• Online Access: https://hdl.handle.net/10356/161682
• Institution: Nanyang Technological University

Extrusion of neutrophil extracellular traps (NETs), a fundamental host innate immune defense against pathogens, has recently been linked to cancer resistance to immunotherapy and distant metastasis. These findings highlight interesting areas of cancer-elicited inflammation and potential therapeutic...