Smart nano-PROTACs reprogram tumor microenvironment for activatable photo-metabolic cancer immunotherapy

Smart nano-PROTACs reprogram tumor microenvironment for activatable photo-metabolic cancer immunotherapy

Protease inhibitors can modulate intratumoral metabolic processes to reprogram the immunosuppressive tumor microenvironment (TME), which however suffer from the limited efficacy and off-targeted side effects. We report smart nano-proteolysis targeting chimeras (nano-PROTACs) with phototherapeutic ab...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhang, Chi, He, Shasha, Zeng, Ziling, Cheng, Penghui, Pu, Kanyi
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2022
Subjects:
Science::Medicine
Cancer Immunotherapy
Phototherapy
Online Access:https://hdl.handle.net/10356/162219
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/162219

Similar Items