Renal clearable polyfluorophore nanosensors for early diagnosis of cancer and allograft rejection

• Main Authors: Huang, Jiaguo, Chen, Xiaona, Jiang, Yuyan, Zhang, Chi, He, Shasha, Wang, Hangxiang, Pu, Kanyi
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Bioengineering; Diagnostics Tools; Near Infrared
• Online Access: https://hdl.handle.net/10356/162237
• Institution: Nanyang Technological University

Optical nanoparticles are promising diagnostic tools; however, their shallow optical imaging depth and slow clearance from the body have impeded their use for in vivo disease detection. To address these limitations, we develop activatable polyfluorophore nanosensors with biomarker-triggered nanopart...