Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS)
The ubiquitous presence of per- and polyfluoroalkyl substances (PFAS) in various environments has led to increasing concern, and these chemicals have been confirmed as global contaminants. Following the chemical regulatory restrictions imposed, PFAS alternatives that are presumed to be less toxic ha...
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sg-ntu-dr.10356-1622722022-10-11T07:10:49Z Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS) Jia, Shenglan Marques Dos Santos, Mauricius Li, Caixia Snyder, Shane Allen Nanyang Environment and Water Research Institute Engineering::Environmental engineering Analytical Method Development Targeted Analysis The ubiquitous presence of per- and polyfluoroalkyl substances (PFAS) in various environments has led to increasing concern, and these chemicals have been confirmed as global contaminants. Following the chemical regulatory restrictions imposed, PFAS alternatives that are presumed to be less toxic have been manufactured to replace the traditional ones in the market. However, owing to the original release and alternative usage, continuous accumulation of PFAS has been reported in environmental and human samples, with uncertain consequences for ecosystem and human health. It is crucial to promote and improve existing analytical techniques to facilitate the detection of trace amounts of PFAS in diverse environmental matrices. This review summarizes analytical methods that have been applied to and advanced for targeted detection and suspect screening of PFAS, which mainly include (i) sampling and sample preparation methods for various environment matrices and organisms, and quality assurance/quality control during the analysis process, and (ii) quantitative methods for targeted analysis and automated suspect screening strategies for non-targeted PFAS analysis, together with their applications, advantages, shortcomings, and need for new method development. 2022-10-11T07:10:49Z 2022-10-11T07:10:49Z 2022 Journal Article Jia, S., Marques Dos Santos, M., Li, C. & Snyder, S. A. (2022). Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS). Analytical and Bioanalytical Chemistry, 414(9), 2795-2807. https://dx.doi.org/10.1007/s00216-022-03905-y 1618-2642 https://hdl.handle.net/10356/162272 10.1007/s00216-022-03905-y 35132477 2-s2.0-85124270535 9 414 2795 2807 en Analytical and Bioanalytical Chemistry © 2022 Springer-Verlag GmbH Germany, part of Springer Nature. All rights reserved. |
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Engineering::Environmental engineering Analytical Method Development Targeted Analysis Jia, Shenglan Marques Dos Santos, Mauricius Li, Caixia Snyder, Shane Allen Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS) |
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The ubiquitous presence of per- and polyfluoroalkyl substances (PFAS) in various environments has led to increasing concern, and these chemicals have been confirmed as global contaminants. Following the chemical regulatory restrictions imposed, PFAS alternatives that are presumed to be less toxic have been manufactured to replace the traditional ones in the market. However, owing to the original release and alternative usage, continuous accumulation of PFAS has been reported in environmental and human samples, with uncertain consequences for ecosystem and human health. It is crucial to promote and improve existing analytical techniques to facilitate the detection of trace amounts of PFAS in diverse environmental matrices. This review summarizes analytical methods that have been applied to and advanced for targeted detection and suspect screening of PFAS, which mainly include (i) sampling and sample preparation methods for various environment matrices and organisms, and quality assurance/quality control during the analysis process, and (ii) quantitative methods for targeted analysis and automated suspect screening strategies for non-targeted PFAS analysis, together with their applications, advantages, shortcomings, and need for new method development. |
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Nanyang Environment and Water Research Institute |
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Nanyang Environment and Water Research Institute Jia, Shenglan Marques Dos Santos, Mauricius Li, Caixia Snyder, Shane Allen |
format |
Article |
author |
Jia, Shenglan Marques Dos Santos, Mauricius Li, Caixia Snyder, Shane Allen |
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Jia, Shenglan |
title |
Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS) |
title_short |
Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS) |
title_full |
Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS) |
title_fullStr |
Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS) |
title_full_unstemmed |
Recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (PFAS) |
title_sort |
recent advances in mass spectrometry analytical techniques for per- and polyfluoroalkyl substances (pfas) |
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2022 |
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https://hdl.handle.net/10356/162272 |
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1749179186216435712 |