A sensitive and specific fluorescent RT-LAMP assay for SARS-CoV‑2 detection in clinical samples

• Main Authors: Ooi, Kean Hean, Liu, Mengying Mandy, Moo, Jia Rong, Nimsamer, Pattaraporn, Payungporn, Sunchai, Kaewsapsak, Pornchai, Tan, Meng How
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Bioengineering; Diagnostics; COVID-19
• Online Access: https://hdl.handle.net/10356/162367
• Institution: Nanyang Technological University

The raging COVID-19 pandemic has created an unprecedented demand for frequent and widespread testing to limit viral transmission. Reverse transcription loop-mediated isothermal amplification (RT-LAMP) has emerged as a promising diagnostic platform for rapid detection of SARS-CoV-2, in part because i...